Haplogroup H

Comment

Comment by Peiternella Suzzanna Hymen on April 14, 2010 at 3:10am

What animal DNA do you work with Maria? Interesting to see that all mtDNA for our beloved dogs is wolf. Do you know if the wolf DNA is region specific or if they can place a particular breed? Your job must be rather interesting.This DNA stuff is so fascinating and a big time waster along with distance running for me....not enough time in a day for two compulsive hobbies.
Can I ask what your mutations are, if you don't mind. I am building an H database and getting data of the papers on Phylotree -link below, another good site
.http://phylotree.org/
join and place your details and see if you get any matches, plus you may get an idea of what your sub clade maybe! Good luck

Comment by Maria on April 13, 2010 at 11:13pm

No company as I work in a genetics lab and I did it myself. Just that I work with non human DNA and I can't find a DB to enter the mutations of HVR2. HVR1 show I'm H and like you say, I don't think HVR2 will show enough resolution for a sub group. I'll check tomorrow at work. Thanks!!!

Comment by Peiternella Suzzanna Hymen on April 13, 2010 at 10:03pm

Please excuse my poor reading -I meant to say 'what' mutations not 'want' :)

Comment by Peiternella Suzzanna Hymen on April 13, 2010 at 10:01pm

Hi Maria, Did your testing company inform you want haplogroup your are in? If not then you can look up want mutations you have or not have on this link below.
http://www.genebase.com/blog/?p=30
Explore the rest of the site to...it is great for us Hs also.
Sometimes HVR1 and HVR2 are not detailed enough to define what sub clade you are in. Cheers

Comment by Maria on April 13, 2010 at 4:00pm

Hi Suzzanna,

I have done HVRI and II and I can't find a database to find out the haplogroup using HVRII. I was able to find http://nnhgtool.nationalgeographic.com/classify/index.html for region I. Can you suggest a database for region II?

Comment by R vd Berg on April 4, 2010 at 12:13am

Dear Peiternella, I've let my mtDNA checked by www.dnaheritage.com
It took them 3 months to get these results. Alastair Greenshields is the principle overthere. Do you have doubts about their methodes? I've paid 130 USD for this mtDNA research. Thank you for your time

Comment by Jeff Marquardt on April 3, 2010 at 8:34pm

Hi Peiternella,
It looks like the H3 project at FTDNA will be putting me in "Cluster D", as I match the others there who also share 408A. As of yet though, I'm still unassigned.

I followed your earlier advice regarding Genbank and my accession number is GU997629. I haven't been there yet to try to figure out BLAST and see if my data has been posted, but it should be available now. If you'd still like an email, let me know, otherwise feel free to add the info to your database.

Comment by Peiternella Suzzanna Hymen on April 3, 2010 at 8:28pm

Hi Jeff, your results are classic H3 like mine with standard mutations that most share.I have 12811C( with 2 others on the database) which appears to be a yet undefined sub branch of H3 . Maybe your 408A mutation will one day define another sub-branch of H3 but I have yet to see it my data base(still got heaps to put on it-waiting for partner to finish a programme so I will not have to manually do it)
Would you be will to also give me your mutations details via email to please. This is confidential as I will not be using your name or publishing papers etc(to dumb for that Lol). Cheers

Comment by Jeff Marquardt on April 3, 2010 at 7:45pm

My results were similar, albeit missing 3 in HVR1. I was tested at FTDNA who declared me H3.

HVR1: 16093C 16519C

HVR2: 263G 309.1C 315.1C 408A

Coding Region: 750G 1438G 4769G 6776C 8860G 15326G

Comment by Peiternella Suzzanna Hymen on April 3, 2010 at 7:21pm

Hi R vd Berg, first off, who did your mtDNA sequence?
I am currently building an H database so I can get an understanding of how and why some companies determine what sub clade we are in (or in my case not).23and me are not so reliable for mtDNA defining, I have been told.
Your mutations are interesting as to be a H1 you need (or so I believed with FTDNA) the mutation 3010A -you do not have this!. But you do have 16189C which is one of the mutations that defines H1f along with 4452C, 7309C, 9066G, 16093C, which you do not have, also.This is why I would like to know what company you used if you do not mind me asking, please. All your other mutations are pretty standard for most of us Hs, However, you have an insertion in 16193c to16193.1C which, so far, I have not come across.
Have you submitted your mtDNA results to Genebank. All very simple, a lovely man called Ian Logan will do it for you. Copy and paste link and you will see how to go about it. http://www.ianlogan.co.uk/Submission.htm.
May have permission to add your data to my database (if you have not submitted to Genebank that is)?
Cheers

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